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Szerző:Dunlap, Norma
Cím:Medicinal chemistry / Norma Dunlap, Donna M. Huryn
Megjelenés:New York, NY ; London : Garland Science, Taylor & Francis Group, LLC, [2018], cop. 2018
Terjedelem:xii, 495 p. : ill. ; 28 cm
Megjegyzések:Mutató: p. [477]-495.
Bibliográfia a fejezetek végén
1., Historical perspective and overview of drug discovery. - 2., Drug discovery : hit and lead identification. - 3., Lead optimization : drug-target interactions and the pharmacophore. - 4., Lead optimization : properties optimized and medicinal chemistry strategies. - 5., The process of developing a drug from an optimized lead. - 6., Receptors, ion channels, and transporters as drug targets. - 7., Enzymes as drug targets. - 8., Protein-protein interactions and lipid structure interactions as drug targets. - 9., DNA and RNA as drug targets. - 10., Anti-cancer drugs. - 11., Antiviral and antifungal agents. - 12., Antibacterial and antiparasitic drugs. - 13., Drugs acting on the central nervous system
Medicinal Chemistry teaches essential concepts by focusing on how the field is actually practiced, melding real-world research experience with basic principles and modern methods. Written by practicing medicinal chemists, this textbook is intended for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry. Pre-medical or pre-pharmacy students and professionals entering the drug discovery field will also find it a useful reference. Building on a foundation of synthetic organic chemistry and structural biology, the book interweaves therapeutics, case studies, historical context, and techniques for discovering, developing, and optimizing new drugs. Chapters are richly illustrated and include problems and annotated journal references with accompanying exercises and answers.
ETO jelzet:54:615(075.8) 615.001.7(075.8) 615.015.3(075.8)
NLM jelzet:2018 E-812 QV 745
LC jelzet:RS403
ISBN:978-0-8153-4556-5 (fűzött) 0-8153-4556-9 (fűzött)
Tárgyszavak:Gyógyszerészeti kémia
Gyógyszerfejlesztés
Gyógyszerhatóanyag-leadó rendszerek
Pharmaceutical chemistry.
Drug development.
Drug delivery systems.
Drug Discovery
Drug Delivery Systems
Egyéb nevek:Huryn, Donna M.
Borító:
LelőhelyTémaEgyéb tematikus jelzetJelzetÉvszámKötetStátuszElőjegyz.Mellékletek
DEENK Élet- és Természettudományi Könyvtár [1. em.]QV745 D97Kölcsönözhető00
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